diff --git a/extension/extension.js b/extension/extension.js
--- a/extension/extension.js
+++ b/extension/extension.js
@@ -730,6 +730,10 @@
     sendPortMessage("settings", "openKRunnerSettings");
 });
 
+addRuntimeCallback("settings", "subsystemStatus", (message, sender, action, sendReply) => {
+    sendReply(subsystemStatus);
+});
+
 chrome.runtime.onMessage.addListener(function (message, sender, sendResponse) {
     // TODO check sender for privilege
 
diff --git a/extension/options.css b/extension/options.css
--- a/extension/options.css
+++ b/extension/options.css
@@ -14,6 +14,10 @@
     display: none;
 }
 
+.not-supported {
+    display: none !important;
+}
+
 .tabbar {
     display: block;
     padding: 0;
diff --git a/extension/options.js b/extension/options.js
--- a/extension/options.js
+++ b/extension/options.js
@@ -79,6 +79,14 @@
     });
 }
 
+function subsystemStatus() {
+    return new Promise((resolve, reject) => {
+        sendMessage("subsystemStatus", null, (reply) => {
+            resolve(reply);
+        });
+    });
+}
+
 function saveSettings(cb) {
     var settings = {};
 
@@ -158,6 +166,28 @@
             mprisEx.disabled = !mpris.checked;
         });
 
+        subsystemStatus().then((status) => {
+            document.querySelectorAll("[data-requires-extension]").forEach((item) => {
+                let requiredExtension = item.dataset.requiresExtension;
+                let requiredMinimumVersion = Number(item.dataset.requiresExtensionVersionMinimum);
+
+                if (requiredExtension && !status.hasOwnProperty(requiredExtension)) {
+                    console.log("Extension", requiredExtension, "is not supported by this version of the host");
+                    item.classList.add("not-supported", "by-host");
+                    return; // continue
+                }
+
+                if (requiredMinimumVersion && !isNaN(requiredMinimumVersion)) {
+                    let runningVersion = status[requiredExtension].version;
+                    if (runningVersion < requiredMinimumVersion) {
+                        console.log("Extension", requiredExtension, "of version", requiredMinimumVersion, "is required but only", runningVersion, "is present in the host");
+                        item.classList.add("not-supported", "by-host");
+                        return; // continue
+                    }
+                }
+            });
+        });
+
         // auto save when changing any setting
         // TODO can we do that on closing, or does it not matter how often we do chrome storage sync thing?
         document.querySelectorAll("input[type=checkbox]").forEach(function (item) {