diff --git a/find-modules/FindPythonModuleGeneration.cmake b/find-modules/FindPythonModuleGeneration.cmake
--- a/find-modules/FindPythonModuleGeneration.cmake
+++ b/find-modules/FindPythonModuleGeneration.cmake
@@ -132,6 +132,12 @@
     add_library(Python::Libs${version} UNKNOWN IMPORTED)
     set_property(TARGET Python::Libs${version} PROPERTY IMPORTED_LOCATION ${GPB_PYTHON${version}_LIBRARY})
     set_property(TARGET Python::Libs${version} PROPERTY INTERFACE_INCLUDE_DIRECTORIES ${GPB_PYTHON${version}_INCLUDE_DIR})
+
+    if (NOT GPB_PYTHON${version}_SITEARCH)
+      execute_process (COMMAND "${GPB_PYTHON${version}_COMMAND}" -c "import sys; from distutils import sysconfig;sys.stdout.write(sysconfig.get_python_lib(plat_specific=True,standard_lib=False))"
+        OUTPUT_VARIABLE GPB_PYTHON${version}_SITEARCH)
+    endif()
+
   endif()
 endmacro()
 
@@ -423,6 +429,7 @@
 
     foreach(pyversion ${_pyversions})
         message(STATUS "Found dependencies for python${pyversion}, generating bindings")
+        message(STATUS "Python${pyversion} install dir: ${GPB_PYTHON${pyversion}_SITEARCH}")
 
         execute_process(COMMAND "${CMAKE_COMMAND}"
           "-DPYTHON_UMBRELLA_MODULE_FILE=${CMAKE_BINARY_DIR}/py${pyversion}/${GPB_PYTHONNAMESPACE}/__init__.py"
@@ -446,7 +453,7 @@
             OUTPUT_NAME "${GPB_MODULENAME}")
 
         if (GPB_SIP_DEPENDS MATCHES PyKF5)
-          set(_kf5_python_prefix ${CMAKE_INSTALL_PREFIX}/lib/python${pyversion${pyversion}_maj_min}/${GPB_INSTALL_DIR_SUFFIX})
+          set(_kf5_python_prefix ${GPB_PYTHON${pyversion}_SITEARCH})
         else()
           set(_kf5_python_prefix ${CMAKE_BINARY_DIR}/py${pyversion})
         endif()
@@ -456,7 +463,7 @@
         )
 
         install(DIRECTORY ${CMAKE_BINARY_DIR}/py${pyversion}/${GPB_PYTHONNAMESPACE}
-            DESTINATION lib/python${pyversion${pyversion}_maj_min}/${GPB_INSTALL_DIR_SUFFIX})
+            DESTINATION ${GPB_PYTHON${pyversion}_SITEARCH})
         install(FILES ${sip_files} "${CMAKE_CURRENT_BINARY_DIR}/sip/${GPB_PYTHONNAMESPACE}/${GPB_MODULENAME}/${GPB_MODULENAME}mod.sip"
           DESTINATION share/sip/${GPB_PYTHONNAMESPACE}/${GPB_MODULENAME}
         )